In 2004, the Catholic population, proportionately the largest in Scotland and second largest in Great Britain, was 165,100 from a total population of 633,000 (26.1%). In 2012 the diocese was served by 65 parish priests, 7 assistant priests and 13 deacons in across its 74 parishes. There are currently 35 retired priests from the diocese and 4 who reside in parishes in the diocese. The area of the diocese is .
The following is a list of the Bishops of Motherwell:
* Edward Douglas+ (appointed 7 February 1948 – resigned 9 February 1954)
* James Scanlan+ (appointed 23 May 1955 – translated to the Archdiocese of Glasgow+ 29 January 1964)
* Francis Thomson+ (appointed 8 December 1964 – resigned 14 December 1982)
* Joseph Devine+ (appointed 13 May 1983 - resigned Thursday 30 May 2013)
* Joseph Toal+ (appointed 29 April 2014 – present; previously Bishop of Argyll and the Isles Diocese from October 2008 - April 2014 and Apostolic Administrator of Motherwell from 30 May 2013 - 29 April 2014)
There are currently 75 parishes and 74 churches in the Diocese which are served by 72 priests and 13 deacons.
Krysztof Garwolinski, administrator of St Patrick's, Wishaw is chaplain to the Polish community.
Joseph Vembadamthara is chaplain to the Syro Malabar Community and is an assistant priest at St Cuthbert's, Hamilton.
On Wednesday 24 July 2013, Leo Cushley+, a priest of the diocese of Motherwell was appointed the Archbishop of St Andrew's and Edinburgh. Cushley was ordained in 1985 by Devine in St John the Baptist Church, Uddingston before serving in the Cathedral, St Serf's, Airdrie and St Aidan's, Wishaw. Since 1992 he has been a diplomat for the Vatican and held the post as head of the English-language section of the Vatican's Secretariat of State.
Cardinal Thomas Winning+, a priest of the Diocese born in Wishaw was Archbishop of Glasgow from 1974 until his death in 2001.
The 75 Parishes in the Diocese are split in 9 deaneries.
# Airdrie+ Deanery - :dean, Rev. R. Breslin
# Central Deanery - :dean, Rev. J. Grant
# Coatbridge+ Deanery - :dean, Rev. V. Lockhart
# East Kilbride+ Deanery - :dean, Rev. I. Boyle
# Hamilton+ Deanery - :dean, Rev. B. Lamb
# Motherwell+ Deanery - :dean, Rev. R. Kane
# Northern Deanery - :dean, Rev. K. O'Brien
# Rutherglen+ Deanery - :dean, Rev. P. Hennessy
# Wishaw+ Deanery - :dean, Rev. H. Kelly
Due to a shortage in priests, a number of parishes have begun to share parish priests including, Larkhall (St Mary's), Blackwood (St John's), Hamilton (St Ninian's, St Cuthbert's, St Mary's and St Paul's), Motherwell (Cathedral and St Luke's), Coatbridge (St Stephen's and St Bernard's), Holytown (Christ the King), New Stevenston (St John Bosco's), Airdrie (St Margaret's and St Serf's), Baillieston (St Bridget's and St Francis of Assisi'), Bellshill (Sacred Heart and St Gerard's), Cambuslang (St Bride's and St Cadoc's Halfway), Wishaw (St Thomas' and St Patrick's), Wishaw (St Aidan's), Cleland (St Mary's), Stepps (St Joseph's), Craigend (St Dominic's).
There are 11 priests and 1 deacon who serve as school chaplains to the high schools in the diocese.
There is also a chaplain to the main hospitals in the diocese, Monklands (Colin Hughes), Wishaw (Michael Brown) and Hairmyres (Liam O'Connor).
Our Lady of Good Aid Cathedral was first built in 1900 and became the cathedral of the new diocese of Motherwell in 1948. The current Cathedral Administrator is Thomas Millar. The parish of the cathedral was linked with the parish of St Luke's Motherwell in 2011.
: Rt Rev Mgr Thomas Millar
: Very Rev Edward Glackin (11 August 1934 - 18 January 2016)
: Very Rev Cornelius O'Leary
: Very Rev William Dunnachie
: Very Rev Denis Keane
: Very Rev Patrick McGovern
: Very Rev Herbert Flack
: Very Rev Patrick O'Hare
: Very Rev Patrick O'Sullivan
: Very Rev Thomas Gibbons
: Very Rev Timothy Brosnan
: Very Rev Michael Ryan
: Very Rev Noel Carey
: Very Rev Andrew Reen
: Very Rev William O'Sullivan
: Very Rev Niall Hayes
: Very Rev John B Healy
: Very Rev Michael Walsh
: Very Rev Humphrey O'Mahony
: Rt Rev Thomas O'Hare
: Rt Rev John McIntyre
: Very Rev Joseph Clements